Discussion Questions: How DNA Evidence Works

  • DNA fingerprinting is only the first step in proving a suspect's DNA matches crime scene DNA. What is the second, and why is it important?
  • What does non-coding DNA mean?
  • Why is it important to create DNA profiles that include VNTRs from both maternal and paternal chromosomes in a chromosome pair?
  • Why do you think DNA profiles produce discrete bands on a gel, instead of long solid streaks? [Hint: Think about what makes an individual band travel down the gel during electrophoresis.]
  • Examine the DNA "ladders" on the gels. What do you think they are, and why do you think they are there?
  • What can DNA profiles be used for, besides proving guilt or innocence in a courtroom?